Wake up bitter mouth, mouth like boiling water tasteless, if the short-term appearance of dietary structure can be adjusted, pay attention to oral hygiene, etc., if the long-term appearance, should go to the hospital in a timely manner. Waking up with a bitter mouth, mouth like boiling water tasteless may be caused by gastrointestinal or gallbladder disease, treatment methods are as follows. 1. If it appears in the short term, patients can be advised to take a light, easy-to-digest, regular diet, do not eat spicy, greasy and other foods. Pay attention to oral hygiene, to develop a good habit of gargling and brushing more often. 2. If it occurs for a long time, you should go to the hospital to find out the cause of the disease. If it is caused by gastrointestinal diseases, you should take acid-suppressing drugs or mucous membrane protectants under the guidance of the doctor. If it is caused by gallbladder disease, should be under the guidance of the doctor to take the neutralization of bile drugs (such as magnesium aluminum carbonate, aluminum thiogluconate, etc.). There are many causes of bitter mouth tastelessness, it is recommended to go to the hospital to improve the relevant examination, to clarify the cause of the disease, and to be targeted treatment.