Whether unilateral 2 lung nodules can be operated at the same time is mainly related to the size of the lung nodules and their physical status, which can be operated at the same time if they meet the surgical indications, but not at the same time if they do not. If the examination results show that the lung nodule is relatively small, which has little effect on the patient’s respiration, and the patient’s physical condition is good, without cardiopulmonary dysfunction, without other systemic complications, without infiltrative metastasis in other parts of the nodule and with small resection area, then unilateral two lung nodules can be operated at the same time. However, if the patient’s cardiopulmonary function is poor, or the resection area of the nodule is large, if a single resection will cause a large lung tissue loss, then there is no indication for simultaneous resection of two pulmonary nodules, and they cannot be surgically removed at the same time. It is recommended that a detailed further examination should be performed before surgery, and then the doctor should be consulted according to the results of the examination, and then the surgery should be performed according to the doctor’s instructions.