The cost of cranial repair surgery is a concern for many patients. Many patients are often caught in a dilemma because they need the surgery to bring health to their bodies, but they are also worried about the high cost of skull repair surgery and do not want to put a heavier burden on themselves and their families because of their family’s financial problems. In fact, the patient’s worry is a bit superfluous. Although the skull is an important organ, cranial repair is a routine neurosurgical procedure and does not belong to the category of difficult surgery. For experienced doctors, it is a breeze and the risk is not too high. As for the price of surgery, it cannot be equated with commercial products. Some of the skull defects are large, some are medium, and some are small, and the cost varies greatly. The cost of cranial repair varies from patient to patient, and no matter which surgical option a patient chooses, each surgeon will do his or her best to bring the ideal surgical result to the patient and create a healthy foundation for the patient in a lucrative manner. The choice of repair material is also critical in determining the cost of the procedure. The widely used traditional titanium mesh is a relatively inexpensive material, so many local hospitals and general hospitals choose this material to perform surgery for their patients, and patients are more than satisfied with the price. However, titanium mesh material has obvious clinical defects. Common cold and heat sensitivity reactions can leave patients with chronic pain symptoms after surgery, and some patients take long-term medication to link the pain sensation. PEEK, the material of choice for cranioplasty, is an internationally recognized “replacement” material for cranial bone and is therefore relatively expensive. As the saying goes, “You get what you pay for,” and that’s not a bad thing. In terms of biocompatibility, PEEK is far superior to titanium mesh, with elastic modulus, strength, insulation, and stability similar to that of autologous cranial bone, and the use of three-dimensional shaping to create an ancient plate that precisely matches the original cranial structure is the key to successful surgery.