Pituitary adenomas are usually classified into two types: those that secrete hormones, which are called “functional pituitary adenomas”, and those that do not, which are called “non-functional pituitary adenomas”. Non-functioning pituitary adenomas: radiotherapy may be used if necessary. If there is still a significant amount of non-functioning pituitary adenoma remaining after transsphenoidal approach surgery, radiotherapy may be used to prevent further growth of the remaining tumor. A number of different radiotherapy modalities have also been developed for the treatment of pituitary tumors, including gamma knife and three-dimensional conformal intensity-modulated radiotherapy to minimize the side effects of radiotherapy on normal tissue. If only a very small amount of residual tumor is found after surgery, the lesion usually does not change significantly for several years, and you can have regular reviews by having regular MRIs of the saddle area. If the tumor shows signs of further growth, treatment will be necessary. If the residual tumor remains unchanged, you can continue to have regular checkups without worrying. Functional pituitary tumors: postoperative drug therapy For residual tumors after resection of functional pituitary adenomas such as acromegaly, Cushing’s disease or prolactinoma, the excessive secretion of hormones in the patient’s body can be controlled by drug therapy. Under the professional guidance of an endocrinologist, individualized drug therapy can supplement or even replace radiotherapy. In summary If residual tumor is found after resection surgery, radiotherapy is not necessarily needed. Doctors will formulate individualized treatment plans according to the nature of the pituitary tumor and the specific conditions of the residual tumor. Patients do not need to worry too much.