MTX refers to methotrexate, a chemotherapeutic drug. methotrexate embryocide mainly refers to the use of methotrexate in ectopic pregnancy to inhibit the proliferation and hyperplasia of trophoblast cells, but because it can also inhibit normal cells, it will generally lead to gastrointestinal discomfort, liver and kidney function damage, bone marrow suppression and other side effects. 1. gastrointestinal discomfort: some patients may experience nausea, vomiting, abdominal pain, diarrhea, and decreased appetite after applying methotrexate. The symptoms include: nausea, vomiting, abdominal pain, diarrhea, decreased appetite, etc. Serious patients may also have symptoms of gastrointestinal bleeding; 2, liver and kidney function damage: methotrexate embryonic killing may cause transaminases and alkaline phosphatase to rise, leading to symptoms of liver function damage. It may also antagonize the corresponding metabolites within the antibody, causing abnormal kidney metabolic function, and may even lead to proteinuria, hematuria, and other kidney function damage; 3, bone marrow suppression: the application of methotrexate to kill embryos may lead to a decrease in white blood cells, red blood cells, platelets, anemia, abnormal coagulation function, etc., and in severe cases, there may also be a lack of white blood cells and granulocytes; 4, other: in addition, methotrexate to kill embryos The side effects are also manifested as causing allergic rash, hair loss and other symptoms, and at the same time, it will make the patient’s resistance decrease and easily co-infection, leading to diseases such as stomatitis and mouth ulcers.