Nevus is pigmented mole. Pigmented nevus laser treatment a few times can not be removed patients can take other treatment methods, such as cryotherapy, surgical treatment and other methods of treatment. It is recommended to choose the appropriate treatment method under the guidance of the doctor. 1. Cryotherapy: It is by freezing liquid nitrogen on the surface of tissues, so that the local tissues will be frozen instantly, which will make nevus cells and pigment cells necrotic, so as to achieve the purpose of getting rid of nevus. 2. Surgical treatment: surgical excision and suture, surgical excision combined with autologous skin flap transfer to repair the defect, surgical excision combined with autologous or allogeneic skin patch repair and other surgical methods. Nevus pigmentosus is a benign swelling produced by abnormal proliferation of local pigment cells in the skin, and the process of repairing the damage by repeated laser treatments may lead to malignant changes. Therefore, if the pigmented nevus has not been completely removed after several laser treatments, it is recommended to go to a regular medical institution and choose a suitable and effective method of treatment under the guidance and advice of a specialized doctor.