Diabetes is currently occurring in China at a rate of 3,000 per day and is characterized by an earlier age of onset, affecting the quality of life of the nation and shortening the lives of patients. As we all know, one of the reasons for the occurrence of diabetes is the obvious family genetic tendency, the genetic gene is like a “seed”, the seed must be in the “soil”, “water”, “air” and other suitable environment to germinate. The seed must be in the right environment of “soil”, “water” and “air” in order to germinate. In the case of diabetes, the genes that determine diabetes, like the seed, will produce diabetes in the right environmental factors. A large body of scientific evidence proves that acquired lifestyle changes are the main influencing factor in the development of diabetes in carriers of the genetic gene for diabetes. Studies have proven that there is a significant difference in the level of insulin secretion between diabetic genetic carriers and non-genetic carriers under the same living environment and with the same diet. That is, insulin secretion is significantly increased in early diabetic genetic carriers, resulting in pre-meal hypoglycemic response and invariably increased meal intake, coupled with lack of exercise, resulting in weight gain, while the total amount of insulin required is proportional to body weight. Thus, the total amount of insulin increases, but the insulin receptors are correspondingly reduced and the sensitivity is weakened, and insulin has to be secreted tens of times higher than normal to maintain normal blood sugar. Over time, the insulin-secreting cells are overburdened until the pancreatic islet function cannot maintain normal metabolism and diabetes occurs. In today’s world, due to improved living conditions, eating and drinking, especially children with a family history of diabetes, obesity occurs early and at an early age, making the onset of type 2 diabetes much earlier. One of our data shows that: the incidence of overweight children aged ≤18 years is 17.6%, the incidence of obesity is 5.6%, and the incidence of childhood obesity in some economically developed cities is as high as 20%. With the increase of obesity, the incidence of diabetes is on the rise. Data show that the incidence of diabetes in moderately obese people is four times higher than normal, and highly obese people can be up to 30 times higher. According to a children’s hospital in Beijing, the number of hospitalizations for pediatric diabetes has increased more than threefold in recent years, mostly in adolescents with type 2 diabetes. We must acknowledge the reality that poor lifestyles cause obesity and lead to the development of diabetes. Especially in the diabetic population, obesity is often used as one of the testable indicators for the occurrence of diabetes when it is not yet possible to accurately predict the diabetes gene. Therefore, as diabetic patients, especially diabetic parents, in order to avoid the occurrence of diabetes in their children, they should first establish a good lifestyle for their children, avoid eating and drinking a lot, and pay attention to strengthening physical exercise so that they can keep their weight in the ideal range, ideal weight (kg) = (height cm – 105). For children who are already overweight or obese, they should promptly consult an endocrinologist specializing in endocrinology and diabetes to work out together a plan to reduce weight and control risk factors, and give a reasonable and healthy scientific diet to maintain normal weight without affecting the children’s nutrition and growth and development. At the same time, physical activity should be gradually increased, with no less than 30 minutes of moderate physical activity per day. For obese children who have developed type 2 diabetes, it is more important to control their weight to the normal range while medication is administered. In children with obesity in early type 2 diabetes, after reasonable dietary management and weight control, it is possible for insulin to be withdrawn after the indicators reach the standard, so that the body can return to a healthy state. In conclusion, the consequences of obesity in children are serious, and the consequences of obesity in children of diabetic patients are even more serious. For the sake of children’s health and future, we remind parents, medical workers and the whole society to work together to keep children away from obesity and diabetes.