If a single oral dose of 1800 mg of mifepristone is taken, no serious adverse effects have been reported, but if the intake greatly exceeds the dose, attention should be paid to the possibility of signs of adrenal failure. Mifepristone is distributed with the blood in the organs and tissues after internal administration, with the liver and kidneys being higher and the kidneys predominant, and therefore these organs are also responsible for poisoning. Studies have shown that if a single oral dose of 1800g is taken, no serious adverse effects have been seen, but if the dose is far exceeded, adrenal failure may occur, and long-term overdose of mifepristone may also damage the cells of the zona fasciculata of the adrenal cortex. Mifepristone is now commonly used for emergency contraception 72 hours after unprotected sex or contraceptive failure, or in combination with prostaglandin drugs for termination of pregnancy within 49 days of menopause. More common adverse reactions, such as uterine bleeding, lower abdominal pain, nausea, vomiting, fatigue, back pain, and dyspepsia. It should be contraindicated in patients who are allergic to the product, patients with cardiac, hepatic and renal diseases and adrenocortical insufficiency, those who have contraindications to the use of prostaglandin drugs, those who are pregnant with IUDs or suspected of having ectopic pregnancies, and those who have a history of abnormal bleeding or who are undergoing concomitant anticoagulant therapy. The drug is recommended to be used under the guidance of a specialized doctor.