Painful red tongue due to discomfort of systemic conditions, such as endocrine and metabolic disorders, and vitamin B deficiency. So, how do patients diagnose whether they have painful red tongue syndrome? The following is a brief introduction: Except for tongue inflammation such as map tongue, furrowed tongue, tongue papillitis, or trigeminal neuralgia, etc., which causes tongue pain, clinically patients complaining of pain in the tongue without detecting positive signs, histopathology without features, and normal tongue tenderness and mobility are called painful tongue syndrome. This syndrome often disappears temporarily when the patient concentrates on a certain task, and there is burning-like pain, dull pain, or pins-and-needles pain in the tongue, but it has no effect on language or diet. In addition to tongue pain, other oral mucosa also has burning pain, then it is called burning mouth syndrome. The whole body condition discomfort, such as endocrine, metabolic disorders, vitamin B deficiency and other reasons, especially menopausal women often complain of irregular tongue pain, and accompanied by other parts of the body discomfort. When patients suspect that they have a “tumor” in the pharynx, or in some cases when they see their own red, swollen and hypertrophic lobe papillae, contour papillae, fear, followed by discomfort or pain in the tongue, in order to carefully observe the condition and frequent tongue extension, mouth opening activities, so that the tongue root muscle fatigue, discomfort, thereby increasing the discomfort of the tongue. Mild tongue pain may also be caused by local stimulation, such as sharp tooth tips, unsuitable bracket substrates, etc.; or two different metal restorations on the same side of the mouth, and weak current stimulation when the upper and lower jaws are opposite each other.