Why schizophrenia requires prolonged maintenance treatment

  Can a person with schizophrenia be completely cured? No relapse, like normal people? How long do I need to take medication to be completely cured? Such questions are universal and it is difficult to have an accurate answer. Modern medicine confirms that schizophrenia is a chronic and prolonged disease that is repeatedly aggravated or worsened, and only a small number of patients can remain cured or basically cured, and about 1/5 of patients who have one episode of remission do not have an episode for the rest of their lives. The risk of relapse is five times greater in those who interrupt medication than in those who continue medication.  Those with recurrent or worsening episodes may experience personality changes, decreased social functioning, and present clinically as varying degrees of disability, requiring long-term hospitalization or repeated admissions. According to statistics, nearly 50% of patients with schizophrenia have attempted suicide, and at least l0% of patients eventually die by suicide.  In addition, patients with schizophrenia are more likely to suffer unintentional injuries than the general population and have a shorter average life expectancy. Due to ongoing advances in modern therapeutics, long-term maintenance medication can result in social remission, i.e., some social functioning, in approximately 60% of patients. Obviously maintenance treatment is of great importance to maintain the social functioning of patients.  The treatment period for schizophrenia is long, and maintenance treatment requires close cooperation among physicians, family members, and patients. According to the results of the first domestic survey on medication adherence of schizophrenia outpatients completed in 2007, the current medication adherence of schizophrenia patients is unsatisfactory. Thirty percent of patients and family members admitted to stopping, reducing, or refusing to take their medication during the treatment process. The figures from the physician group were even more pessimistic, with physicians saying that 40% of patients had stopped, reduced or refused to take their medication, and another quarter had forgotten to take their medication.  What can be done to improve patients’ medication adherence? By providing certain interventions for patients and families with schizophrenia, choosing medications with better efficacy and safety, changing the treatment route, and improving communication with patients and their families, treatment interruption rates can be greatly reduced and relapse rates lowered.  The following points should be learned by patients and their families.  1, regular review in the hospital: in general, should be reviewed once a month, if there are special circumstances can be seen at any time. Regular review is good for timely detection of changes in the patient’s condition and problems in the course of drug therapy, so that timely adjustments can be made to improve the patient’s compliance.  2, choose the best dosage form suitable for patients, such as those who do not want to take oral tablets can use water, drops, oral disintegration tablets, long-acting injections or slow release 3, create a good environment: give them a quiet and regular living environment, timely guidance of patients’ psychological problems, motivate and accompany them to participate in activities, exercise and improve the patients’ life, work ability and social adaptability, to have confidence in patients, so that They should learn to take care of themselves.  4, pay attention to identify the signs of relapse: insomnia, mood changes, dazed and frothy, unresponsive, lazy life, etc., or the re-emergence of the original mental symptoms, the original can actively take medication, suddenly deny the disease, refuse to take medication, etc., should be timely to find a physician to deal with to avoid relapse or reduce the severity of relapse.  5. Respect patients and avoid discrimination.