Rheumatic diseases in the broad sense are a group of diseases mainly involving joints and the surrounding muscles, soft tissues and skeletal system that require medical treatment, including rheumatoid arthritis, ankylosing spondylitis, gout, systemic lupus erythematosus, osteoarthritis, etc. There may be damage to internal organs. Rheumatism in a narrow sense refers to rheumatic fever, and rheumatoid arthritis is one of the clinical manifestations of rheumatic fever. The rheumatism commonly referred to in life refers to painful diseases of joints, muscles and other soft tissues, including rheumatoid arthritis and osteoarthritis (degenerative arthritis), etc. Rheumatoid arthritis is usually seen in adolescents and has a rapid onset, with sore throat, fever and leukocytosis, and the involvement of large joints of the limbs is common. If prevention and treatment are not complete, the heart may be repeatedly damaged, resulting in heart valve adhesions and increased scarring, resulting in chronic rheumatic heart disease; serum anti-“O” is positive, while rheumatoid factor is negative. Rheumatoid arthritis is treated with aspirin, streptococcal infection control and other anti-rheumatic treatments. Rheumatoid arthritis can develop at any age, but is more common in women, with an incidence of about 0.3% in China. It is mainly involved in the proximal interphalangeal joints, metacarpophalangeal joints, wrists, knees, feet and other joints, and is often accompanied by morning stiffness, swelling and pressure pain in the active phase. The disease may also present with systemic manifestations of multiple organ involvement, including rheumatoid nodules on the skin or internal organs, anemia, pericarditis, interstitial lung lesions, and multiple peripheral neuropathies. Those with extra-articular lesions suggest a more severe disease. Treatment should be considered comprehensively, and active and correct comprehensive treatment can lead to remission in more than 80% of rheumatoid arthritis patients. Therefore, early diagnosis and treatment is the key to a good prognosis for rheumatoid arthritis. Common drugs used for treatment are: ① Non-steroidal anti-inflammatory drugs (NSAIDs) such as anti-inflammatory pain, ibuprofen, naproxen, diclofenac, meloxicam, celecoxib, etc. ②Disease ameliorating drugs (DMARDs) such as methotrexate, on top of which one or two others are used, such as salazosulfapyridine (SASP), chloroquine, gold preparations, ralston, azathioprine (AZA), leflunomide (LEF), etc. Blood routine, liver and kidney function should be checked regularly during the drug administration to prevent adverse drug reactions. ③Glucocorticoids, which can rapidly reduce joint pain and swelling, can be given in acute attacks of arthritis, or in severe patients with heart, lung, kidney and other organ involvement, with short-acting hormones, the dose of which is adjusted according to the severity of the disease. Small doses of hormones can be used as a “bridge” before the onset of DMARDs, or as a short-term measure when NSAIDs are unsatisfactory. The latest biologic agents, such as anti-tumor necrosis factor receptor fusion protein, and the home-made Beneficep, have been used for the treatment of rheumatoid arthritis and have good efficacy in improving the disease and preventing bone destruction. In conclusion, adequate and reasonable treatment should be carried out as early as possible in the early stage of rheumatoid arthritis, limited by space, the above can only briefly introduce, if any patients need in-depth consultation can come to our department to understand and consult.