Calf external fixation frame infection may be caused by pathogenic bacteria invasion, poor immunity of the body and other infections, the treatment mainly includes conservative treatment and surgical treatment and so on. 1. Conservative treatment: if the patient has less exudation from the nail eye area, the skin temperature is not high, no fluctuation feeling under the skin and other symptoms of mild infection, conservative treatment can be chosen. Conservative treatment is mainly anti-infection treatment, which requires oral or intravenous antibiotic drugs, such as cephalosporin or penicillin antibiotics. At the same time, the wound should be treated with dressing change. The above drugs need to be used under the guidance of the doctor, avoid self-medication. 2. Surgery: If the patient has symptoms of serious infection such as more exudation from the wound site, obvious redness and swelling, elevated skin temperature, etc., or the possibility of osteomyelitis is considered, surgical intervention is needed to remove the external fixation bracket. Surgical procedures include open window decompression and debridement, dead bone removal, etc. Postoperative anti-infection treatment is still required. Specific surgical methods need to be decided by the doctor after comprehensive evaluation. The above drugs need to be used under the guidance of a doctor.