Nephrotic syndrome with nausea and vomiting, need to take drugs to protect the gastric mucosa treatment, if necessary, need to receive hemodialysis treatment. 1. Drug therapy: patients need to take drugs with gastric mucosa protection and antiemetic drugs, such as proton pump inhibitors, omeprazole, pantoprazole and esomeprazole; antiemetic drugs, such as domperidone tablets and metoclopramide. 2. Hemodialysis: patients need to go to regular hospitals to receive renal function and urine routine examination, so as to understand the kidney disease, if the kidney disease develops to the stage of uremia, it is necessary to receive hemodialysis treatment to get rid of excess metabolites, which can help reduce nausea and vomiting symptoms. In addition, the use of the above medications carries certain risks and should be used under the supervision of a specialist. It is recommended that patients with nausea and vomiting associated with nephrotic syndrome go to the hospital in time and follow the doctor’s instructions for standardized treatment.