Causes of medial ankle pain include trauma, osteophytes, nerve or blood vessel compression, ankle tube syndrome, and joint inflammation. 1. Trauma: Commonly, there are sprains, car accident injuries, etc., which lead to obvious pain caused by damage to soft tissues or bones, accompanied by symptoms such as swelling of ankle and pain aggravated by activities. 2. Osteomalacia: induced by aging, obesity or long-term wear and tear, etc., manifested as intermittent pain on the inner side of the ankle, swollen joints, difficulty in climbing stairs or squatting. 3. Ankle tube syndrome: caused by bone fracture, varicose veins, etc. Typical features are pain in the sole of the foot or the inner side of the ankle, relieved after resting, and deformity of the foot in severe cases. 4. Nerve or blood vessel compression: such as cysts in the ankle area, lumbar disc herniation, etc., which cause pain caused by obstruction of nerve conduction or blood circulation in the ankle area. 5. Joint inflammation: including osteoarthritis, gouty arthritis, etc., due to inflammation stimulation caused by the inside of the ankle pain, joint stiffness, elevated skin temperature. In addition, flat feet, heel valgus, etc. can also cause pain on the inside of the ankle. The cause of the pain cannot be determined by this symptom alone. If the pain is recurrent or lasts for a long period of time, it is recommended that you seek medical attention as soon as possible.