The frequency of medication change after atrial defect interventional occlusion surgery should follow the doctor’s instructions, usually the first day, and then every 1~3 days, and should pay attention to avoid strenuous exercise. Compared with traditional surgery, atrial defect interventional sealing surgery has the advantages of less trauma and faster healing. Usually, it is necessary to change the medication on the first day after the surgery and observe the healing of the incision, and then change the medication every 1~3 days, and if the incision is healing well, the last medication change can be done on about the 7th day after the surgery. Since the incision is usually made at the root of the thigh, the blood vessels need to be punctured at the incision, so compression is needed to stop bleeding after the operation, and attention should be paid to avoiding the stimulation of the wound by strenuous exercise. The frequency of postoperative dressing changes should be determined by the clinician according to the condition of the patient, and the above frequency is for reference only.