The length of time needed for male azoospermia to be cured is considered to be related to the cause of the disease and the severity of the disease, etc. If the patient is congenital azoospermia, it is generally incurable; if the patient is azoospermia caused by genitourinary aspects, it generally takes about 1~6 months to get significantly better through antibiotic treatment, surgical treatment and so on. 1. Congenital factors: If the patient has chromosomal abnormality and hereditary disease, such as Crohn’s syndrome, etc., it is generally incurable. 2. Genitourinary system: the patient is caused by genitourinary infection, after symptomatic treatment with antibiotics such as azithromycin, levofloxacin, etc., it can be significantly improved in about 1~2 months. All the above drugs need to pay attention to the side effects and adverse reactions of drugs, please use the above drugs under the guidance of a doctor. If it is considered to be caused by bilateral vasovaginal obstruction, through vasovaginal obstruction recanalization surgery, usually 2~3 weeks after the surgery will be improved. If it is caused by bilateral varicocele, there will also be improvement usually about six months after the operation. The cure time for male azoospermia is not certain, it is recommended to take the doctor’s advice in regular hospitals and to have regular checkups. In your daily life, keep a good mood and good habits.