Drinking too much wine has a bad stomach and diarrhea, considered as alcohol stimulation of the gastrointestinal mucosa caused by inflammatory changes in the mucosa, can be adjusted through dietary adjustments such as a light diet, take omeprazole and other drugs for relief and treatment. 1. Dietary adjustments: abdominal pain and diarrhea can be relieved through dietary adjustments. Diet should be light, eat more easily digestible food, such as millet porridge, steamed bread, noodles and so on. Quit smoking and drinking, and avoid spicy and stimulating foods such as chili, pepper, garlic, ginger, onion, etc., so as not to stimulate the gastrointestinal mucosa, causing abdominal pain, diarrhea and other symptoms. 2. Medication: (1) proton pump inhibitors: such as omeprazole, esomeprazole, pantoprazole, etc., can be irreversibly combined with the proton pump, thereby inhibiting the secretion of gastric acid, reducing the stimulation of gastric acid on the gastrointestinal mucosa, relieving abdominal pain, acid reflux, belching (burping), bloating, nausea, diarrhea and other symptoms. (2) Mucosal protectants: such as gefalconate, aluminum thioglycollate, bismuth potassium citrate, etc., can form a layer of protective film on the surface of the gastrointestinal mucosa, so as to protect the gastrointestinal mucosa to a certain extent from the stimulation of gastric acid, food and so on, to improve the symptoms of diarrhea, abdominal distension, abdominal pain and so on. Drinking too much wine stomach bad diarrhea, can also be relieved by local massage and other ways, it is recommended to consult a doctor in order to clarify the diagnosis, under the guidance of the doctor for targeted treatment.