Severe hair loss may be androgenetic alopecia, patchy baldness, etc. It needs to be treated according to the cause of the disease, usually using medication and hair transplantation to increase hair. 1. Androgenetic alopecia: androgenetic alopecia is mainly related to heredity and androgen, which is characterized by thinning of the hair on the top of the forehead and gradual decrease or thinning of the hair, often accompanied by the symptom of increased oil secretion of the scalp. Minoxidil tincture can be used topically and oral medication can be applied at the same time. Male patients can take finasteride tablets orally and female patients can take spirocycloheximide orally for treatment, and hair transplantation can be used to increase the hair when the hair loss is controlled or stabilized. 2. Patch baldness: Patch baldness is mainly related to genetic, endocrine, autoimmune and other factors, mainly manifested as sudden patchy hair loss. Local topical mometasone furoate ointment, minoxidil tincture, etc., and at the same time, the joint application of oral drugs, such as prednisone, vitamin B complex, cystine tablets and other drugs to promote hair growth. All of the above drugs need to be used under the guidance of a professional doctor, avoid self-medication. Hair loss may also have other causes, it is recommended to go to the hospital in a timely manner to improve the examination, clear cause of the disease to give targeted treatment.