Biochemical indicators: generally, the main liver function, once a month after the start of treatment, three times in a row, and then once every three months as the condition improves; virological indicators: in short, including HBV-DNA and hepatitis B five, generally tested once every 1-3 months after the start of treatment, and then once every 3-6 months; Zhao Wenxia, Department of Spleen, Gastrointestinal, Hepatobiliary Diseases, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine, according to the needs of the condition and the type of oral antiviral drugs, regular tests of blood routine, cardiac enzymes and kidney function are required, and for patients treated with interferon, thyroid function, blood glucose and autoantibodies should also be tested regularly.