1, the contraction of the skin piece After implantation, with the vascular buds into the skin piece, fibroblasts develop into fibroblasts, and some of the fibroblasts are myofibroblasts, for the thin skin piece its myofibroblasts increase rapidly, and also slow to subside, and in the full-thickness or with the subcutaneous vascular network of the skin piece, the myofibroblasts disappear quickly, so the long-term contraction of thin skin piece is also large, and the scarring of the skin piece is also heavy, and the full-thickness or with the subcutaneous vascular network of the skin piece is very small, and the mobility of the skin piece is also large. In full-thickness or subdermal vascularized flaps, the long-term contraction is small and the flaps are more mobile. Overall, the thinner the slice, the higher the survival rate, but the long-term shrinkage is also large; the slice’s abrasion resistance is poor. The thicker the slice, the higher the survival requirements, the slice’s shrinkage is low, the slice’s abrasion resistance is large, and there is a certain degree of mobility with the deep tissue. The dermal vascular network skin sheet wrapping to have a certain pressure, fixed for a long time, but because of easy to superficial skin and part of the dermis necrosis, shedding, and skin blisters, macules, hyperpigmentation, affecting the appearance of the skin, so the current clinical substitution of subcutaneous vascular network of the skin flap with a tibial flap. In the early postoperative period it itself has intact blood circulation and can be broken off at an early stage. Not only to preserve the advantages of thick skin, but also to overcome the shortcomings of the traditional skin flap late break time. 2, the regeneration of nerves The feeling is poor for about one year after skin grafting, so it is important to pay attention to protection against burns, scalds, frostbite and mechanical trauma, apply grease and strengthen functional exercise. In sensory recovery, pain and touch sensation are recovered earlier, and hot and cold sensation is later. The sympathetic nerve function of full-thickness skin grafts can be regenerated, and localized sweating is possible, but incomplete, so that the grafted skin pieces do not obtain the same quality as normal skin. Medium-thickness skin grafts do not contain sweat glands, so there is very little sympathetic nerve regeneration. 3, the color of the changes in the skin after transplantation, often due to hyperpigmentation, so that its color is darker than the surrounding skin. Although the skin donor area with similar texture is selected, it is impossible to prevent its pigmentation. After a period of time, the pigmentation may fade to some extent. Exposure to sunlight and ultraviolet rays induces melanocytes to produce larger melanin particles and the skin becomes darker in color. Therefore, avoid sun exposure and the use of UV-blocking skin creams after free skin grafting, and wear wide-brimmed hats, gloves, and long sleeves to minimize hyperpigmentation. 4, accelerate the maturation process of the transplanted skin piece It is very important to wear an elastic sleeve after limb implantation. Without the protection of the elastic sleeve, significant burning and stinging pain, congestion and hemorrhagic blister formation may occur after limb sagging and activity. The action of the elastic sleeve will result in faster maturation of the skin flap and scar tissue, and the skin graft site will be softer sooner.