An enema will not flush down the appendiceal fecal stone. Conservative or surgical measures are needed, taking into account the patient’s specific condition. The formation of appendiceal fecaliths is related to the special anatomy of the appendix. In daily life, if the patient has diarrhea or eat improperly, the food residues form fecal stone, may be accompanied by intestinal peristalsis into the lumen of the appendix, called appendiceal fecal stone. Since the appendix is a blind organ in the human body, and the lumen of the appendix is thin, with a diameter of a few millimeters. Appendiceal fecaliths can be formed when food debris enters the appendiceal lumen and cannot be expelled. In terms of site and effect of the enema, the enema is unable to wash down the appendiceal fecal stone. The effect of appendiceal fecaliths may lead to increased pressure in the appendiceal lumen, which may predispose to acute and chronic appendicitis and other pathologies. Clinically, it is necessary to use intravenous ceftriaxone sodium, levofloxacin and other antibiotics to eliminate inflammation, and surgical removal of the appendix is recommended. However, the treatment of appendicitis due to fecal impaction by enema is not effective. Therefore, when appendicitis is diagnosed, it should be treated promptly and effectively as prescribed by the doctor.