Wu Mei Pills cannot treat persistent insomnia. Wu Mei Pills belongs to the category of proprietary Chinese medicines, and the ingredients include the flesh of Wu Mei, peppercorns, Huang Lian, Huang Bai and Gui Zhi, etc. The properties are brownish-black to black colored large honey pills. The efficacy of Wu Mei Pills is to clear the upper and warm the lower part of the body, ease the liver and regulate the middle, and can be used to treat abdominal pain, diarrhea, irritability, vomiting, cold hands and feet, and so on. However, the clinic did not find Wu Mei Pills have sedative sleeping effect, so Wu Mei Pills can not treat persistent insomnia, persistent insomnia patients if blindly through the Wu Mei Pills to treat the disease, belong to the typical medicine is not the right evidence. The adverse effects of Umei pills and is not clear, contraindication is pregnant women should not take. Umei pills can not be used privately, need to be under the guidance of a professional doctor to use drugs.