What are the precursor lesions of the lung glands

Lung glandular precursor lesions include atypical adenomatous hyperplasia and adenocarcinoma in situ, which refers to the presence of atypical hyperplasia that is not currently malignant but carries a risk of becoming cancerous. Lung glandular precursor lesions are also known as pre-invasive lesions, in which atypical adenomatous hyperplasia refers to limited atypical hyperplasia of the alveolar wall epithelium, in which the hyperplastic cells differ from normal cells in terms of morphology, size, arrangement, and nuclei morphology; whereas adenocarcinoma in situ refers to atypical hyperplasia of the cells involving the entire glandular epithelium, but not breaking through the basement membrane. Atypical neoplastic hyperplasia and adenocarcinoma in situ do not belong to the range of lung malignant tumors, but precancerous lesions of infiltrative lesions such as bronchioloalveolar carcinoma and peripheral lung adenocarcinoma, i.e., there is a certain risk of malignant transformation. Lung adenomatous precursor lesions mostly appear as pure ground glass nodules, which do not need special treatment, but should be closely followed up and observed because of the risk of malignancy. It is recommended that patients should consult a specialist for timely consultation and follow up or treatment as prescribed by the doctor.