Positive expression of pd-l in ovarian cancer indicates that the patient is sensitive to immunotherapy and can be considered for immunotherapy. Ovarian cancer treatments include surgery, chemotherapy, targeted and so on. If the patient is not suitable for surgery, and when chemotherapy and targeted drugs are not effective, the patient will experience disease progression, which is life-threatening. Positive pd-1 test indicates that the patient is sensitive to immunotherapy, and appropriate immunotherapy drugs can be used to improve the patient’s survival. Immunotherapy also has related adverse reactions, such as immunopneumonia, myocarditis, hepatitis, etc., which should be prevented and treated in a timely manner. Advanced ovarian cancer with positive pd-l expression can also consider immunotherapy combined with targeted and chemotherapy, which can further improve the prognosis. Drugs need to be used under the guidance of doctors, do not blindly use drugs.