Some newborns with cysts on the kidney may have no effect on the baby, but there also exist those that have an effect and cannot be generalized. Newborns are examined and found to have renal cysts, when the renal cysts are all simple renal cysts, with small diameter, clear fluid and slow changes, follow up changes in the size of the cysts can be. With normal renal function, small renal cysts often have little effect on the infant. For larger cysts >4cm in diameter, puncture aspiration and injection of sclerosing agent such as anhydrous ethanol may be considered to prevent recurrence. Cystectomy or even nephrectomy should be considered in patients with huge cysts >500ml in volume, malignant tendency or recurrence after puncture. When newborns have cysts on the kidney, they should go to regular hospitals in time and under the guidance of doctors for targeted treatment.