At present, there is no clinical data to show that entecavir withdrawal for a few days will have an effect, the time for withdrawal to appear to have an effect may be related to the individual situation, the effect of disease control, as well as liver function and other factors. If you are in the early stage of liver disease, you need to insist on taking entecavir, and you can’t stop taking it at will. Even if you stop taking it for a short period of time, it may have a certain effect on the control of your condition and aggravate your condition. If the medication has been used for a relatively long time, and the current condition is relatively stable, and the liver function has basically returned to normal, a short period of drug withdrawal will have little effect. People taking entecavir should know that if they are allergic to the components of the drug need to be prohibited, in lactation, pregnancy need to be used with caution, the specific use of the drug should be carried out in accordance with the doctor’s instructions. The person who has diarrhea, dyspepsia, nausea, vomiting after using the drug can be observed first, if the symptoms are serious, consult a doctor and then stop using the drug in a timely manner. Patients with liver disease taking entecavir should not discontinue the drug at will, and should consult a doctor if they need to discontinue the drug.