Patients with adenomyosis of the uterus after three injections of Goserelin can be given additional injections at a later stage under the supervision of the doctor, but they should be aware of the adverse effects of the drug. Adenomyosis refers to the invasion of endometrial glands and mesenchyme into the myometrium of the uterus. It is a common cause of secondary dysmenorrhea and infertility in women, and it also tends to lead to excessive menstruation and prolonged menstrual periods. Clinically, adenomyosis can be treated with gonadotropin-releasing hormone agonists, such as injectable leuprolide acetate microspheres or goserelin. It is injected subcutaneously on the first day of menstruation and every 28 days for a total of 3 to 6 injections. Generally, patients may experience amenorrhea during the 2nd month of use, which can relieve symptoms of dysmenorrhea. During the use of gonadotropin-releasing hormone agonists, there is a possibility of adverse reactions, such as hot flashes, decreased libido, vaginal dryness, bone loss and other menopausal symptoms. If the medication is used for a longer period of time, you can supplement with tibolone or take hypospadias estrone plus medroxyprogesterone to increase estrogen levels and prevent the onset of vascular symptoms and bone loss in a hypoestrogenic state. Adenomyosis patients after three injections of Goserelin later whether to play again, need to consult the doctor in time to decide under the guidance of the doctor, the above drugs need to strictly comply with the doctor’s instructions to take, can not be arbitrarily used on their own medication.