Prostate-specific antigen 5.40 refers to total prostate-specific antigen 5.40 μg/ml, and its normal reference value is in the range of 0~4 μg/ml. the presence of mildly high may be related to prostate hyperplasia,, prostatitis, anorectal examination, and prostate cancer. Total prostate-specific antigen is one of the more specific markers for prostate cancer. When prostate cancer is present, its tissues will release this antigen, which will be significantly elevated and can be used for the early auxiliary diagnosis of prostate cancer. When the total prostate-specific antigen is 4~10μg/ml, prostate cancer can be suspected, but further examination is needed, such as prostate MR and prostate puncture biopsy. In addition, an increase in total prostate-specific antigen of varying degrees and duration can also be seen after prostatitis or benign hyperplasia, anal fingerprinting, cystoscopy and other examinations. So don’t worry too much about the high total prostate-specific antigen, we suggest to follow the doctor’s advice to improve further examination, treatment or therapy with the help of the doctor.