One side of the face hurts when you bite your teeth may be caused by apical periapical inflammation, temporomandibular joint disorder disease, etc., as follows. 1. Periapical inflammation: local inflammatory oozing from the periapical area, tissue edema, the affected tooth has a floating sensation, early contact and occlusal pain, with the development of the disease, the pain can be aggravated, spontaneous, persistent, throbbing pain. 2. Temporomandibular joint disorder: the lesion involves the temporomandibular joint and biting muscle system, chewing pain, accompanied by joint movement popping or murmur, joint movement disorder, abnormal opening movement and other symptoms. There may be other reasons for the pain of biting on one side of the face, so it is recommended to go to the hospital in time to clarify the cause of the disease and then carry out targeted treatment.