Common treatments for intrahepatic cholestasis include medication, surgery, etc. The cause of intrahepatic cholestasis may be different for each individual, and the specific treatment will be decided by the doctor after evaluation. 1. Medication: If the intrahepatic cholestasis is caused by virus-induced liver damage, then anti-viral medications, such as the anti-hepatitis B drug tenofovir, need to be given; ursodeoxycholic acid capsules are preferred for treatment of cholestasis during pregnancy. 2 Surgery: large intrahepatic bile duct stones caused by cholestasis, then need to be treated by surgical removal of stones or resection of the liver, etc.; malignant tumors of the liver caused by obstruction, need to expand the resection of the tumor tissue; diffuse or giant liver cancer can not be surgically resected, cirrhosis of the patient with liver failure, liver transplantation can be considered. Patients with intrahepatic cholestasis should actively seek medical treatment and cooperate with doctors, do not self-medicate or use other ways to avoid delaying the condition, drugs should be applied under the guidance of doctors.