The pain between vertebrae and sacrum is related to ankylosing spondylitis, sacroiliac arthritis, and trauma to the sacral area. 1. Ankylosing spondylitis: it mainly involves sacroiliac joints, spine and hip joints, and the tendency of flexion deformity and bony ankylosis can appear rapidly after violating the spine and joints. Inflammation of sacroiliac joint can cause pain in sacrum. 2. Sacroiliac arthritis: it is a kind of aseptic inflammation that occurs in sacroiliac joints, and the low back pain caused by strain is limited fixed site pain, not accompanied by radiating pain, usually one side of the sacroiliac joints, or both sides of the sacroiliac joints can be seen. 3. Sacral trauma: Sacral pain can occur when the sacrum is injured in the course of sports. Sacral pressure pain is obvious and relieved after rest. There may be other reasons for the pain between the vertebrae and the sacrum, and it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.