The black marks left by mosquito bites can be observed first, and if necessary, medication and laser treatment can be chosen. 1. Observation: black marks from mosquito bites usually disappear gradually over time, so it is recommended that the patient can be observed first, without special treatment. 2. Medication: patients can follow the doctor’s instructions to use drugs for topical application to promote the elimination of black marks as soon as possible, such as tretinoin cream, hydroquinone cream, etc., in order to reduce the local color deposition. 3. Laser treatment: If the mosquito bite left black marks more serious, long-term can not subside, you can choose to improve the black marks through laser treatment, after the operation need to pay attention to sun protection. Mosquito bites leave black marks if you choose drugs or laser, be sure to choose a regular hospital, follow the doctor’s instructions to take a standardized treatment program, not private treatment, so as not to lead to adverse consequences.