Prostate cancer is a common malignant tumor in men, and the common symptom after bone metastasis is bone pain, which can be improved through systematic treatment with drugs and surgery for prostate cancer patients and symptomatic treatment for bone pain.
1. Systematic treatment:
(1) Endocrine therapy: drugs such as abiraterone, enzalutamide, dalorubicin and so on can be used to reduce the androgen level in the body. At the same time, it can also inhibit the binding of androgen receptor and androgen, so as to exert anti-tumor effects, and then reduce the destructive effect of tumor on bone and reduce pain symptoms.
(2) Testicular resection surgery: prostate cancer is an androgen-dependent tumor, and androgen reduction can be achieved by removing the testicles, which can also reduce the destructive effect of the tumor on the bone, thus reducing the pain.
(3) Molecular targeted therapy: angiogenesis inhibitors and kinase inhibitors can be used to achieve anti-tumor effects through inhibiting angiogenesis, inhibiting signaling pathways, and so on, so as to achieve the effect of reducing bone pain, including bevacizumab, sorafenib, sunitinib and so on.
2. Symptomatic treatment:
Use pain relieving drugs according to the principle of cancer pain, including mebuprofen, codeine, morphine, pethidine hydrochloride, etc.
Patients with prostate cancer bone metastasis pain are recommended to go to regular hospitals, and all drugs should be used according to the doctor’s instructions.