Liver cancer CNLC stage IIB is not very serious compared with the advanced stage, and the condition can still be effectively controlled after treatment, but the prognosis of liver cancer is relatively poor, and timely treatment is recommended. Hepatocellular carcinoma is a kind of liver malignant tumor disease, which can be staged by combining China’s specific national conditions and practical accumulation, and the staging scheme of Chinese hepatocellular carcinoma is known as CNLC, while stage IIB refers to the patient’s physical activity status of 0~2, liver function Child-PughA/B grade, the number of tumors in the body is ≥4, and there is no vascular thrombus and extrahepatic metastasis through imaging examination. Liver cancer CNLC stage IIB belongs to intermediate stage, and according to relevant guidelines, it is recommended that patients should prefer hepatic artery cannula embolization chemotherapy to achieve the purpose of inhibiting tumor growth, as well as allowing tumor cells to undergo necrosis and apoptosis due to ischemia and hypoxia, which can improve the prognosis of the disease, and in addition, patients can also consider surgical resection or systemic anti-tumor therapy. The overall prognosis of liver cancer is relatively poor, but compared with advanced liver cancer, liver cancer in the middle stage of its development is not so serious. However, no matter what stage of the disease they are in, liver cancer patients need to carry out individualized treatment according to their conditions in order to prolong their survival period. It is suggested that once diagnosed with liver cancer, individuals should receive standardized treatment as soon as possible and should not be negligent in order to avoid delaying their condition.