If a patient with advanced lung cancer has swollen feet, the cause of swollen feet should be determined and targeted treatment should be carried out. Late stage lung cancer patients will suffer from systemic depletion and malnutrition, resulting in loss of nutrients in the blood, which will cause severe hypoproteinemia and swelling of the whole body, especially in the lower limbs. In this case, adequate nutrition, including enteral nutrition, parenteral nutrition and albumin infusion to improve the colloid osmotic pressure of blood, is needed to improve the swelling of feet. If lung cancer patients have heart dysfunction or heart failure in advanced stage, symptomatic treatment should be given to lung and heart, such as strengthening heart and improving respiratory function, which can mostly reduce the swelling of both lower limbs. Because the lower extremities are the farthest from the heart, the blood or water from the lower extremities cannot easily return to the heart when the heart is not functioning, which will cause edema of the lower extremities. In addition, patients with lung cancer are in hypercoagulable state at the same time, so if thrombosis occurs in both lower limbs, thrombolytic treatment should be performed to improve the blood return to both lower limbs.