The causes of wasting in diabetic patients should be considered from the following aspects: 1. A part of diabetes will show the typical three more and one less symptoms, where the less is the appearance of significant weight loss. Diabetes itself can cause weight loss because high blood sugar can cause dehydration; 2. Diabetes cannot make good use of blood sugar, which can lead to protein loss, so it can lead to weight loss. 3. Certain hypoglycemic drugs have an effect on weight, for example, metformin, GLP-1 agonists and other drugs can cause weight loss. But if weight loss occurs, further screening is needed to see if other problems arise that make the patient appear wasted, as follows: 1. For example, certain common diabetes can easily lead to the appearance of infectious diseases, and infectious diseases can consume energy leading to wasting; 2. Diabetes is prone to decreased resistance and can lead to tuberculosis and other conditions. The chronic or infectious diseases and diabetes complications mentioned above can also lead to wasting, so you should seek medical attention as soon as possible to clarify the cause of wasting.