The symptoms of COPD include: 1. common symptoms: cough, coughing, shortness of breath, dyspnea, and the aggravation of dyspnea will lead to severe carbon dioxide retention, resulting in acidosis and shock; 2. systemic symptoms: fatigue, weakness, which may induce tumor, osteoporosis, and cardiovascular disease; 3. acute exacerbation symptoms: increased dyspnea, increased sputum, and pus sputum, requiring reasonable inhalation of bronchodilators, glucocorticoids, and antibiotic therapy to relieve symptoms; 4. advanced symptoms: severe impairment of right heart function leading to systemic edema.