Erosive blisters are herpes that rise above the skin and contain watery fluid. Blister formation is mostly the result of inflammatory reactions, such as those caused by bacteria, viruses, parasites (scabies), or allergic reactions, and commonly includes aspergillosis, herpes-like dermatitis, and herpes zoster. The lesions of pemphigus are characterized by large blisters on normal-looking skin and mucous membranes with epidermal peeling, occurring in folds of the skin, and are most often seen in middle-aged people. Herpes-like dermatitis and herpes zoster, on the other hand, are polymorphic lesions. The differential diagnosis of erosive blisters: 1. Herpetiform aspergillosis occurs mostly in the elderly, and the basic damage is thick-walled tension blisters or hemorrhagic blisters that do not easily rupture and heal easily after rupture. The spine relaxation sign is negative and mucosal damage is rare. Histopathological examination is subepidermal herpes, and direct immunofluorescence examination of the lesions shows basement membrane bands of band fluorescence due to 1gG and (or) C3 deposition. 2, Herpes-like dermatitis damage is polymorphic, clusters of tense mung bean to cherry-sized thick-walled blisters with negative spine release sign. The blisters are located under the epidermis on histopathological examination. Direct immunofluorescence examination of the lesions showed dermal papillary cis-granular IgA deposits.