If anal papilla enlargement is accompanied by infection, it can be treated with metronidazole. You can also use potassium permanganate warm water sitz bath to help clean and promote the circulation of the skin at the anus. If accompanied by anal fissure, sinusitis, hemorrhoids and other anal diseases, the cause of the disease should use the appropriate drugs. Anal papilla hypertrophy is a common benign tumor of the anus, with the gradual increase of the anal papilla, may appear with the discharge of stool out of the anus, repeated prolapse, so that the local secretion increased and other symptoms. If the anal papilla hypertrophy is combined with anaerobic bacterial infection, metronidazole can be used for anti-infection treatment. Daily use of 1:5000 concentration of potassium permanganate warm water sitz bath, promote the recovery of the condition. If accompanied by hemorrhoids can use Ma Yinglong hemorrhoid cream treatment, if accompanied by anal fissure can use nitroglycerin ointment treatment. If you need to use drugs, you need to use under the guidance of a doctor’s diagnosis.