If vaginal bleeding and abdominal pain occur during non-menstrual period, blood HCG or urine pregnancy test should be performed to confirm pregnancy. If pregnancy is diagnosed, it may be due to miscarriage or ectopic pregnancy, which should be clarified by negative ultrasound and progesterone test. If it is a pre-eclampsia, it should be treated with fertility preservation therapy, and if it is an ectopic pregnancy, it should be treated promptly. If the pregnancy test is negative to exclude pregnancy, it is necessary to clarify the corresponding gynecological diseases that can cause the situation, and it is necessary to carry out gynecological ultrasonography, blood routine, cervical screening, hysteroscopy and other related examinations to clarify whether there are ovarian cysts, uterine submucosal leiomyoma, endometrial polyps, cervical inflammation, cervical intraepithelial neoplasia, cervical malignant tumors, etc., which will lead to the appearance of non-menstrual bleeding and abdominal pain, and according to the results of the different examinations, it is necessary to provide treatment to protect the fetus, if ectopic pregnancy. Depending on the results of the examination, different treatments are given for their different causes.