In general, long-term oral administration of therapeutic doses of warfarin does not affect life expectancy when normal INR values are monitored. Warfarin is a commonly used anticoagulant drug in clinical practice and belongs to the coumarin class. Warfarin is quickly absorbed after oral administration and the binding rate with plasma proteins can reach more than 99%, which is mainly used in clinic to prevent the occurrence of thromboembolic diseases. Application of therapeutic doses does not usually affect life expectancy. It is important to note that warfarin needs to be applied under medical supervision and monitored to maintain INR values in the range of 2.0 to 3.0, and overdose is prone to adverse reactions. The most common is spontaneous bleeding, and the most serious is intracranial hemorrhage, which needs to be taken seriously. It is recommended to seek medical attention as soon as possible when bleeding and other adverse reactions are detected to avoid delaying the condition.