There are two main reasons for soreness and weakness of the whole body after waking up: 1. As a result of strenuous exercise during the day, the body consumes more energy, electrolytes and nutrients, forming more lactic acid and inflammatory metabolites, which, after the appearance of lactic acid, can easily lead to a feeling of soreness and weakness, and inflammatory metabolites can lead to a feeling of soreness and weakness. Since there is more activity during the day, blood circulation is faster and the metabolites produced can be metabolized in a timely and effective manner, so there is no feeling of soreness and weakness. However, after sleeping, the blood circulation slows down and the metabolites produced locally accumulate, resulting in a feeling of weakness and soreness throughout the body. In addition, it is also possible that during the night, the muscles of the body are cooled, which aggravates the feeling of weakness. 2. Due to viral infections caused by cold during sleep at night, especially after influenza virus infection, the metabolites formed by viruses and viruses will affect the muscles and joints of the body, resulting in a feeling of weakness and soreness of the whole body.