The causes of general weakness and special fatigue after waking up include the following: 1, lack of sleep: if you do not get enough rest, it will produce the symptoms of general weakness and special fatigue after waking up; 2, too shallow sleep: if during sleep, the environment may be too noisy or stimulating, always in shallow sleep without effective rest, such symptoms will also occur; 3, systemic diseases: such as insufficient blood supply to the brain, diabetes, hypertension, can affect the quality of sleep of patients. In addition, if the patient has metabolic problems, such as hypothyroidism, the above symptoms can also occur; 4, mental factors: If the spirit is overly nervous and stressed, it will lead to poor sleep quality.