The general weakness and special tiredness after waking up from sleep may be a normal reaction or a state of some diseases. If the time of sleep is too long and the time of entering deep sleep is more, it is possible to have general weakness and special tiredness after waking up, especially in the case of napping, which is more likely to occur. For this situation, proper sleep should be given, avoid sleeping immediately after meals, sleep for one hour is appropriate, and you can wash your face with cold water to promote mental recovery after waking up. In addition, it can also be seen in certain disease states, such as qi and blood deficiency, kidney disease and hypothyroidism, hypokalemia, hypertension, hyperglycemia, lack of blood supply to the brain and heart disease, etc. In these cases, further examination is needed to clarify the specific disease. For example, hypothyroidism requires thyroid function tests, while ion tests are needed for patients with low potassium. For patients with heart disease or brain disease, electrocardiogram and brain MRI are also needed, and for other conditions, relevant tests are done and symptomatic treatment is given in order to achieve better relief.