Severe esophagitis can cause patients to lose weight, esophagitis is mainly due to the esophageal mucosa by chemical substances, such as gastric acid, choline and even radioactive elements, and chemical substances corrosion and mucosal damage. Esophagitis itself inflammation, especially severe esophagitis will lead to the emergence of esophageal stenosis, the patient will have obstacles to eating, choking on food, loss of appetite, loss of appetite, in the long run will lead to the patient’s emaciation. In addition, as most of the patients with esophagitis will have acid reflux at night, resulting in patients not being able to get sufficient and effective rest at night and affecting the patient’s spirit, appetite, absorption, but also aggravate the patient’s fear and anxiety symptoms, which in the long run will also lead to wasting. Therefore, severe esophagitis patients will lose weight.