Liver-Qi offending the Stomach (Liver-Qi gases do not run smoothly and affect the function of the Stomach) syndrome is mainly manifested by distension and pain in the ribs and wounds, belching (hiccups), acid swallowing (swallowing the acid that goes up to the oropharynx in the Stomach), and emotional depression. Liver-Qi against Stomach syndrome refers to the syndrome caused by Liver-Qi stagnation (poor Qi and blood transportation in the liver, emotional depression), and Stomach disharmony (obstruction of the stomach’s function of passing and descending). The main manifestations are distension and discomfort in the stomach and epigastric region and the coats of arms and ribs, walking uncertainly, noisy (a feeling similar to hunger, emptiness with burning in the stomach), belching, acid swallowing, eructation (hiccups), lack of desire for food, depression, good tai shi, or irritability, with a pale red tongue, thin yellow moss, and a stringy pulse. Treatment should be based on the principles of dispersing the liver and relieving depression (treating depression by dispersing the liver’s qi) and harmonizing the stomach, and can be treated with formulas such as Chai Hu Shuo Liver San with additions and subtractions. Chai Hu Shuo Liver Essence is composed of Chai Hu, Paeonia lactiflora, Rhizoma Ligustici Chuanxiong, and Pericarpium Citri Reticulatae, etc. It has the efficacy of dispersing the liver and resolving depression, moving qi and relieving pain (relieving pain by regulating the qi of the human body), and the adverse effects have not yet been clarified. If there is any manifestation of liver qi offending the stomach and medication is needed, one should go to the hospital in time, consult the clinician and follow the doctor’s instructions for treatment.