Normal values of N-terminal brain natriuretic peptide precursor can be categorized according to age: <50 years of age with a normal range of 0-450pg/ml; 50-75 years of age with a normal range of 0-900pg/ml; >75 years of age with a normal range of 0-1800pg/ml. N-terminal brain natriuretic peptide precursor, or B-type natriuretic peptide precursor, which is abbreviated as NT-proBNP, is an important laboratory test for evaluating the presence or absence of heart failure, and is often used in the risk grading of patients with heart failure and the evaluation of the effects of treatment. NT-proBNP is biologically inactive, has a half-life of 120 minutes in vivo, and is highly stable in vitro, making it suitable for clinical testing of cardiac function. However, NT-proBNP levels can be affected by age, gender, and renal clearance. The higher the age, the higher the level of NT-proBNP; the level of NT-proBNP in women is higher than that in men; and the level of NT-proBNP will increase when the renal creatinine clearance rate decreases. Therefore, NT-proBNP should be analyzed in conjunction with clinical symptoms, cardiac ultrasound and electrocardiogram when evaluating the presence or absence of heart failure.