Early symptoms of leukoplakia are mainly in the form of localized lumps or spots, not large in size and irregular in shape, close to round, oval or coin size as a common early manifestation. Vitiligo is also known as vitiligo, which may be caused by genetic factors, autoimmune factors and melanin self-destruction factors. Vitiligo lesions are often milky white or light pink, with a smooth surface and no rash. The early symptoms of vitiligo are mainly localized blocks or spots, the area is not large and irregular shape, close to the round, oval or coin size as a common manifestation. A few patients will have localized itching sensation at the onset. Vitiligo in daily life to reduce the inhalation of harmful gases, pay attention to eat less stimulating food. When the patient appears vitiligo, to go to the hospital in time for consultation, under the guidance of the doctor standardized treatment.