The feeling of obstruction in swallowing things may be caused by pharyngitis and other throat diseases, or it may be caused by reflux esophagitis and other upper gastrointestinal diseases. 1. Pharyngeal diseases: for example, acute attacks of chronic pharyngitis can cause lymphoid follicular hyperplasia of the pharyngeal wall, local mucosal congestion and edema, resulting in local foreign body sensation, sense of obstruction in swallowing. Should maintain oral hygiene, quit smoking and alcohol, you can choose boric acid solution, potassium permanganate solution gargle, at the same time containing iodized throat tablets and other drugs, if there is a secondary bacterial infection, you can take amoxicillin, cephalosporin and other antibiotic treatment. 2. Upper gastrointestinal diseases: for example, reflux esophagitis, gastritis, esophageal cancer, gastric cancer, etc., may also affect the normal peristalsis of the gastrointestinal tract, resulting in a sense of obstruction to swallowing something. It needs to be clarified by gastroscopy and other examinations. For inflammation, acid inhibitors such as omeprazole, mucosal protectants such as magnesium aluminum carbonate, and gastrointestinal stimulants such as mosapride can be given, and antibiotics such as amoxicillin and clarithromycin can be chosen for treatment if Helicobacter pylori infection exists. For tumors, early surgery and radiotherapy and other comprehensive treatment. Swallowing something obstructive feeling need to timely seek medical treatment, under the guidance of the doctor to take appropriate therapeutic measures. Drugs should all be used in accordance with medical advice.