Simple pimples with white pustules on the face usually belong to pustular acne, but there are other possibilities. Acne is a chronic inflammatory disease of the sebaceous glands of hair follicles and can be characterized by lesions such as pimples, papules, pustules and nodules. If acne has white pustules, it belongs to pustular acne, which is also classified as moderate acne. However, if facial acne has white pustules, it can also be acute generalized eruptive pustulosis or pustular psoriasis, often accompanied by fever. Acute generalized eruptive pustulosis is a rare acute eruption characterized by numerous non-follicular sterile pustules on an edematous erythematous base. Pustular psoriasis is a type of psoriasis characterized by a sudden onset of widespread, painful erythematous plaques or thin plaques rapidly covered with numerous pinhead-sized sterile pustules. Patients should keep a good mindset, cooperate with doctors for treatment, and pay attention to skin care and cleanliness.